Makima is a major antagonist in the Chainsaw Man series, being the main antagonist of the Public Security arc. Initially acting as a helpful ally towards the protagonist, Denji, by taking him under her wing and making him as a pet, she is also the leader of the Public Safety Devil Hunter organization who tried her best to make Denji's life happy to the point he tried to find another purpose in life and becoming a happier person compared to what he is in the past due to the suffering that he had endured during his childhood days.